| Rank | Event Name | Total Raised |
| 1 | 2024 Bank of America Chicago Marathon | $2,059,763 |
| 2 | TCS New York City Marathon | $1,524,986 |
| 3 | Bike-A-Thon 2024 | $1,208,152 |
| 4 | Pan Ohio Hope Ride 2024 | $1,073,906 |
| 5 | TCS London Marathon 2024 | $381,290 |
| 6 | 2024 BMW Berlin Marathon | $350,559 |
| 7 | Independence Blue Cross Broad Street Run 2025 2024 | $322,309 |
| 8 | Walt Disney World Marathon Weekend 2024 | $267,919 |
| 9 | Walk and Roll Chicago 2024 | $247,885 |
| 10 | Fighting Cancer to the Coast 2024 | $229,323 |
| 11 | Cycle the South Hope Ride 2024 | $226,153 |
| 12 | United Airlines NYC Half 2024 | $218,613 |
| 13 | Climb to Conquer Cancer of Phoenix 2024 | $204,273 |
| 14 | Bicycles Battling Cancer | $179,553 |
| 15 | Disney Princess Half Marathon Weekend 2024 | $173,143 |
| 16 | Sole Burner Chaseburg | $159,525 |
| 17 | PA Hope Ride Against Cancer Presented By Donegal Insurance Group 2024 | $137,844 |
| 18 | Climb to Conquer Cancer of Flagstaff | $132,235 |
| 19 | Swim For Cancer | $120,511 |
| 20 | Long Beach Marathon | $116,878 |
| 21 | 2024 Disneyland® Half Marathon Weekend 2024 | $116,208 |
| 22 | 2025 runDisney Springtime Surprise Weekend 2024 | $115,863 |
| 23 | Hope On The Slopes At Jay Peak 2024 | $92,564 |
| 24 | El Camino de Santiago | $92,470 |
| 25 | Disney Wine and Dine Half Marathon Weekend | $91,476 |
| 26 | Disneyland Halloween Half Marathon Weekend | $76,904 |
| 27 | TD Five Boro Bike Tour 2024 | $74,441 |
| 28 | Big Sur International Marathon 2024 | $70,038 |
| 29 | Golden Gate Half Marathon | $67,658 |
| 30 | C2C Relay Run 2024 | $64,662 |
| 31 | Napa Valley Marathon, Half Marathon, and 5K 2024 | $59,115 |
| 32 | 2025 Grandma's Marathon and Garry Bjorklund Half Marathon 2024 | $58,850 |
| 33 | 2024 Marine Corps Marathon | $51,351 |
| 34 | The King of Chemo's Great World Record | $50,456 |
| 35 | Surf City Marathon 2025 2024 | $48,124 |
| 36 | Pedal to End Cancer | $40,247 |
| 37 | Irish Life Dublin Marathon | $39,218 |
| 38 | Philadelphia Marathon, Half Marathon, and 8K | $38,783 |
| 39 | Valencia Marathon | $31,627 |
| 40 | 2024 Choose Your Race-DetermiNation Mini Series | $25,216 |
| 41 | 2024 Medtronic Twin Cities Marathon Weekend | $16,906 |
| 42 | Boulderthon DetermiNation Weekend 2024 | $15,437 |
| 43 | Kilimanjaro Climb | $11,165 |
| 44 | 2024 Pittsburgh Marathon Weekend | $5,076 |
| 45 | Pedal to End Cancer VT | $4,447 |
| 46 | 2024 Bike-A-Thon Volunteer Registration | $2,200 |
| 47 | Philadelphia Distance Run | $2,093 |
| 48 | Jackie Schneider Run for Ovarian Cancer Research | $1,105 |
| 49 | Boilermaker Road Race | $553 |
